(4-甲基苯甲酰基)乙酸乙酯合成路线 （共 32 条）
反应条件
lt;(η5-C5H5)Fe(CO)2(THF)gt;+lt;BF4gt;- in dichloromethane T=0°C; 8 h;
参考文献
Dudley, Matthew E.; Morshed, Monzur; Brennan, Courtney L.; Islam, M. Shahidul; Ahmad, M. Syarhabil; Atuu, Mary-Rose; Branstetter, Bryan; Hossain, M. Mahmun
Journal of Organic Chemistry, 2004 , vol. 69, # 22 p. 7599 - 7608
反应条件
1: ethyl methyl carbonate With sodium hydride T=20°C; Inert atmosphere; 2: para-methylacetophenone 4 h; Inert atmosphereReflux;
参考文献
Balamurugan, Rengarajan; Manojveer, Seetharaman
Chemical Communications, 2011 , vol. 47, # 39 p. 11143 - 11145
反应条件
1: polystyrene-supported α-seleno acetate, loading 1.64 mmol/g (COOH) With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 0.5 h; 2: 4-methyl-benzaldehyde in tetrahydrofuran T=-78 - 20°C; 2.5 h; 3: With dihydrogen peroxide in tetrahydrofuran T=20°C;
参考文献
Qian, Hao; Huang, Xian
Synlett, 2006 , # 10 p. 1547 - 1548
反应条件
1: potassium tert-butylate / neat (no solvent) / 2 h / 20 °C 2: bis-triphenylphosphine-palladium(II) chloride / neat (no solvent) / 2 h / 20 °C View Scheme
参考文献
Qian, Hao; Ge, Chunrong; Huang, Xian
Journal of Chemical Research, 2007 , # 3 p. 160 - 161
反应条件
zinc; diisobutylaluminium hydride; palladium 1.) DME; 2.) DME, 0 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Sato, Toshio; Itoh, Toshiyuki; Fujisawa, Tamotsu
Chemistry Letters, 1982 , p. 1559 - 1560
反应条件
1: ethyl 4-methylbenzoate With sodium hydride in benzene Heating; 2: ethyl acetate in benzene 4 h; Heating;
参考文献
Menozzi, Giulia; Merello, Luisa; Fossa, Paola; Mosti, Luisa; Piana, Antonietta; Mattioli, Francesca
Farmaco, 2003 , vol. 58, # 9 p. 795 - 808
反应条件
aluminium trichloride
参考文献
Marguery
Bulletin de la Societe Chimique de France, 1905 , vol. <3> 33, p. 550
反应条件
sodium hydride 1.) DMF, mineral oil, 15 min, 2.) DMF, mineral oil, heating; Yield givenMultistep reaction;
参考文献
Karnik, A. V.; Rane, J. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1998 , vol. 37, # 11 p. 1191 - 1193
反应条件
(i) nBuLi, THF, hexane, (ii) /BRN= 471492/; Multistep reaction;
参考文献
Wierenga,W.; Skulnick,H.I.
Journal of Organic Chemistry, 1979 , vol. 44, # 2 p. 310 - 311
反应条件
Yield given. Multistep reaction;
参考文献
Wladislaw, B.; Marzorati, L.; Uchoa, R. B.
Phosphorus and Sulfur and the Related Elements, 1987 , vol. 32, p. 87 - 90
