(4-甲基苯甲酰基)乙酸乙酯合成路线 （共 32 条）
反应条件
in methanol; tetrachloromethane T=26°C; other proton donating solvents in mixture with CCl4, effect of protic solvents on the keto-enol equilibrium; Product distribution;
参考文献
Zheglova, D. Kh.; Kol'tsov, A. I.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, p. 462 - 465
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 3 p. 513 - 516
反应条件
1: ethanol; methanol. sodium methylate 2: sodium methylate; methanol View Scheme
参考文献
Sistare; Pascual
Anales de la Real Sociedad Espanola de Fisica y Quimica, 1952 , vol. <B> 48, p. 593,595
反应条件
1.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C 1.2: 20 °C 2.1: Mn(OAc)3·H2O / ethanol; water / 6 h / 50 °C View Scheme
参考文献
Wang, Chao; Li, Zhilong; Ju, Yeming; Koo, Sangho
European Journal of Organic Chemistry, 2012 , # 35 p. 6976 - 6985
反应条件
1: 82 percent / p-TosOH / benzene / Heating
2: 70 percent / LiAlH4 / diethyl ether / 2.5 h / Heating
3: 54 percent / pyridinium chlorochromate/NaOAc / CH2Cl2 / 2.5 h / Ambient temperature
4: 1. Mg / 1. THF 2. THF/room temperature/overnight, then 2 h/reflux
5: 77 percent / aq. HCl / acetone / 2 h
6: 1. Mg / 1. Et2O 2. Et2O/room temperature/overnight
7: 50 percent / Jones' reagent / acetone
View Scheme
参考文献
Vig, O. P.; Sharma, S. D.; Soni, B. R.; Sharma, M. L.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 5 p. 353 - 355
反应条件
ytterbium trichloride in ethanol
T=50°C; 24 h;
参考文献
Cai, Lijian; Ji, Xiaofeng; Yao, Zhigang; Xu, Fan; Shen, Qi
Chinese Journal of Chemistry, 2011 , vol. 29, # 9 p. 1880 - 1886
反应条件
hydroxylamine hydrochloride
T=100°C; 0.5 h;
参考文献
Rajender, P. Sarita; Sridevi; Reddy, K. Kondal
Synthetic Communications, 2012 , vol. 42, # 15 p. 2191 - 2200
参考文献
Menozzi, Giulia; Merello, Luisa; Fossa, Paola; Mosti, Luisa; Piana, Antonietta; Mattioli, Francesca
Farmaco, 2003 , vol. 58, # 9 p. 795 - 808
反应条件
piperidine; acetic acid in acetonitrile
RefluxInert atmosphere;
参考文献
Wang, Ying; Yu, Zhi-Hua; Zheng, Hu-Fei; Shi, De-Qing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 38 p. 7739 - 7746
反应条件
1: hydrogen chloride; ethanol; hydrogen sulfide
2: diethyl ether / Erwaermen des Reaktionsprodukts mit Chlorwasserstoff enthaltendem Methanol
3: phosphorus (V)-sulfide; xylene
View Scheme
参考文献
Raoul; Vialle
Bulletin de la Societe Chimique de France, 1959 , p. 1670,1674
反应条件
ammonium acetate
Substitution;
参考文献
Ishida, Yohsuke; Yoshida, Yuhki; Igarashi, Tetsutaro; Sakurai, Tadamitsu
Heterocycles, 2013 , vol. 87, # 8 p. 1691 - 1698
