3,6-二甲基-1,2-苯二酚合成路线 （共 25 条）
反应条件
1: 75 percent / ethanol / 96 h / 25 °C
2: 18 h / Heating
3: 94 percent / aq. HClO4, H2 / Pd/C / ethyl acetate / 1.5 h / 2585.7 Torr
4: 97 percent / aq. HCl / methanol / 4 h / Heating
View Scheme
参考文献
Sinhababu, Achintya K.; Borchardt, Ronald T.
Synthetic Communications, 1982 , vol. 12, # 12 p. 983 - 988
反应条件
Pseudomomas putida UV4; oxygen
Enzymatic reaction; optical yield given as percent ee;
参考文献
Boyd, Derek R.; Sharma, Narain D.; Malone, John F.; Allen, Christopher C.R.
Chemical Communications, 2009 , # 24 p. 3633 - 3635
反应条件
(i) (thermolysis), (ii) aq. H2SO4; Multistep reaction;
参考文献
Zbiral,E. et al.
Monatshefte fuer Chemie, 1960 , vol. 91, p. 331 - 347
反应条件
1: Cu(NO3)2*3H2O
2: aq. HCl / dimethylsulfoxide
View Scheme
参考文献
Schill,G. et al.
Synthesis, 1979 , p. 695 - 697
反应条件
copper; potassium carbonate; glycerol
T=195°C; 8 h;
参考文献
Dallacker; Coerver
1983 , vol. 38, # 10 p. 1243 - 1248
反应条件
potassium carbonate in ethylene glycol
参考文献
The Procter and Gamble Company
Patent: US5965595 A1, 1999 ;
US 5965595 A
反应条件
copper; potassium carbonate; glycerol
T=195°C; 8 h;
参考文献
Dallacker; Coerver
1983 , vol. 38, # 10 p. 1243 - 1248
反应条件
1: 83 percent / K2CO3 / dimethylformamide / 24 h / 100 °C
2: 1.) POCl3 / 1.) 40-45 deg C, 45 min, 2.) r.t., 16 h, then 70 deg C, 6 h
View Scheme
参考文献
Dallacker; Coerver
1983 , vol. 38, # 10 p. 1243 - 1248
反应条件
1: 49.2 percent / K2CO3, Cu, glycerine / 8 h / 195 °C
2: 1.) POCl3 / 1.) 40-45 deg C, 45 min, 2.) r.t., 16 h, then 70 deg C, 6 h
View Scheme
参考文献
Dallacker; Coerver
1983 , vol. 38, # 10 p. 1243 - 1248
反应条件
1: 34 percent / K2CO3, Cu, glycerine / 8 h / 195 °C
2: 1.) POCl3 / 1.) 40-45 deg C, 45 min, 2.) r.t., 16 h, then 70 deg C, 6 h
View Scheme
参考文献
Dallacker; Coerver
1983 , vol. 38, # 10 p. 1243 - 1248
