1,2,3,4-四苄基-beta-d-吡喃葡萄糖合成路线 （共 20 条）
反应条件
toluene-4-sulfonic acid in methanol; dichloromethane T=20°C; 6 h;
参考文献
Fernandez, Caridad; Nieto, Ofelia; Fontenla, Jose Angel; Rivas, Emilia; De Ceballos, Maria L.; Fernandez-Mayoralas, Alfonso
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 5 p. 767 - 771
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; desilylation; 9 h;
参考文献
Berkowitz, David B.; Bose, Mohua; Pfannenstiel, Travis J.; Doukov, Tzanko
Journal of Organic Chemistry, 2000 , vol. 65, # 15 p. 4498 - 4508
反应条件
hydrogenchloride; 3 A molecular sieve; sodium cyanoborohydride in tetrahydrofuran; diethyl ether T=0°C; 1 h;
参考文献
Takeo, Ken'ichi; Okushio, Kazuo; Fukuyama, Katsumi; Kuge, Takashi
Carbohydrate Research, 1983 , vol. 121, p. 163 - 174
反应条件
sodium methylate in methanol Zemplen deacetylation; 5 h;
参考文献
Lu, Wallach; Navidpour, Latifeh; Taylor, Scott D.
Carbohydrate Research, 2005 , vol. 340, # 6 p. 1213 - 1217
反应条件
lithium aluminium tetrahydride; aluminium trichloride in diethyl ether; dichloromethane T=30°C;
参考文献
Das; Mallet; Sinay
Angewandte Chemie - International Edition in English, 1997 , vol. 36, # 5 p. 493 - 496
反应条件
1.1: 78 percent / DMAP / pyridine / 7 h / 60 °C 2.1: NaH / dimethylformamide / 0.17 h / 0 °C 2.2: 82 percent / dimethylformamide / 20 °C 3.1: 88 percent / p-TsOH / CH2Cl2; methanol / 6 h / 20 °C View Scheme
参考文献
Berkowitz, David B.; Bose, Mohua; Pfannenstiel, Travis J.; Doukov, Tzanko
Journal of Organic Chemistry, 2000 , vol. 65, # 15 p. 4498 - 4508
反应条件
1: 78 percent / HOAc / ZnCl2 / 1.5 h / 20 °C 2: 97 percent / NaOMe / methanol / 5 h View Scheme
参考文献
Qu, Boyi; Li, Xiaocen; Guan, Mei; Li, Xun; Hai, Li; Wu, Yong
European Journal of Medicinal Chemistry, 2014 , vol. 72, p. 110 - 118
反应条件
lithium aluminium tetrahydride; aluminium trichloride in diethyl ether; dichloromethane 2 h; Heating;
参考文献
Sen, Asish K.; Banerji, Nilima
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 818 - 823
反应条件
1.1: NaH / dimethylformamide / 0.17 h / 0 °C 1.2: 82 percent / dimethylformamide / 20 °C 2.1: 88 percent / p-TsOH / CH2Cl2; methanol / 6 h / 20 °C View Scheme
参考文献
SHIRE AG; WHOMSLEY, Rhys; ALLAN, Christine Elizabeth; LUKER, Timothy Jon
Patent: WO2014/2039 A1, 2014 ;
反应条件
[Mg2Cl3(THF)y]+*[AlH4-nCln]- in tetrahydrofuran T=70°C; Reduction; 24 h;
参考文献
Szabovik; Medgyes; Antal; Varga; Knott; Liptak
Polish Journal of Chemistry, 1999 , vol. 73, # 6 p. 1003 - 1009
