(R)-(+)-1-(4-吡啶基)乙醇合成路线 (共 26 条)
反应条件
boric acid trimethyl ester; dimethylsulfide borane complex; chiral diphenyl(2-pyrrolyl)methanol in tetrahydrofuran T=0 - 5°C; 0.166667 h;
参考文献
Masui, Moriyasu; Shioiri, Takayuki
Synlett, 1997 , vol. 1997, # 3 p. 273 - 274
反应条件
Candida antarctica lipase B; (η5-C5Ph5)Ru(CO)2Cl; potassium tert-butylate; sodium carbonate in tetrahydrofuran; toluene T=50°C; 20 h;
参考文献
Martin-Matute, Belen; Edin, Michaela; Bogar, Krisztian; Kaynak, F. Betuel; Baeckvall, Jan-E.
Journal of the American Chemical Society, 2005 , vol. 127, # 24 p. 8817 - 8825
反应条件
in water T=35°C; 84 h; nonfermenting baker's yeast Saccharomyces cerevisiae;
参考文献
Rasor, Peter; Ruechardt, Christoph
Chemische Berichte, 1989 , vol. 122, p. 1375 - 1376
反应条件
air; cells of Geotrichum candidum IFO 5767 in water T=30°C; 24 h;
参考文献
Nakamura, Kaoru; Fujii, Mikio; Ida, Yoshiteru
Tetrahedron Asymmetry, 2001 , vol. 12, # 22 p. 3147 - 3153
反应条件
BES buffer; Lipase from Burkholderia cepacia; calcium chloride in acetonitrile T=30°C; pH=7.2; 2 h; Title compound not separated from byproducts;
参考文献
Savile, Christopher K.; Kazlauskas, Romas J.
Journal of the American Chemical Society, 2005 , vol. 127, # 35 p. 12228 - 12229
反应条件
4 A molecular sieve; Lipase from Burkholderia cepacia in 1,4-dioxane T=30°C; 48 h;
参考文献
Savile, Christopher K.; Kazlauskas, Romas J.
Journal of the American Chemical Society, 2005 , vol. 127, # 35 p. 12228 - 12229
反应条件
4 A molecular sieve; subtilisin E in 1,4-dioxane T=30°C; 48 h; Title compound not separated from byproducts;
参考文献
Savile, Christopher K.; Kazlauskas, Romas J.
Journal of the American Chemical Society, 2005 , vol. 127, # 35 p. 12228 - 12229
反应条件
Rhizopus nigricans (sterile potato dextrose medium) in tetrahydrofuran 16 h;
参考文献
Ziffer, Herman; Kawai, Ken-ichi; Kasai, Masaji; Imuta, Mitsuru; Froussios, Cleanthis
Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 3017 - 3021
反应条件
Lipase PS-C in di-isopropyl ether T=35°C; 12.3333 h;
参考文献
Itoh, Toshiyuki; Matsushita, Yuichi; Abe, Yoshikazu; Han, Shi-Hui; Wada, Shohei; Hayase, Shuichi; Kawatsura, Motoi; Takai, Shigeomi; Morimoto, Minoru; Hirose, Yoshihiko
Chemistry - A European Journal, 2006 , vol. 12, # 36 p. 9228 - 9237
反应条件
T=25°C; 48 h; biotransformation using Catharanthus roseus cell cultures in precultured B5 medium;
参考文献
Takemoto, Masumi; Achiwa, Kazuo
Phytochemistry, 1998 , vol. 49, # 6 p. 1627 - 1629