(R)-(+)-1-(4-吡啶基)乙醇合成路线 (共 26 条)
反应条件
phosphate buffer; lipase T=20°C;
参考文献
Laumen, Kurt; Schneider, Manfred P.
Journal of the Chemical Society, Chemical Communications, 1988 , p. 598 - 600
反应条件
sodium hydroxide; Candida rugosa lipase E.(1)C3113 type VII in phosphate buffer T=20°C; pH=7.2; 54 h; Title compound not separated from byproducts.;
参考文献
Bellezza, Francesca; Cipiciani, Antonio; Cruciani, Gabriele; Fringuelli, Francesco
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 24 p. 4439 - 4444
反应条件
sodium hydroxide 75 h; lipase from Pseudomonas sp. (SAM II), phosphate buffer pH 7.0;
参考文献
Seemayer, Robert; Schneider, Manfred P.
Tetrahedron: Asymmetry, 1992 , vol. 3, # 7 p. 827 - 830
反应条件
lipase Amano PS,potassium phosphate buffer T=25°C; 12 h; Yield given;
参考文献
Kawai, Yasushi; Hida, Kouichi; Ohno, Atsuyoshi
Bioorganic Chemistry, 1999 , vol. 27, # 1 p. 3 - 19
反应条件
1: lipase Amano PS / benzene / 48 h / 35 °C 2: lipase Amano PS,potassium phosphate buffer / 12 h / 25 °C View Scheme
参考文献
Kawai, Yasushi; Hida, Kouichi; Ohno, Atsuyoshi
Bioorganic Chemistry, 1999 , vol. 27, # 1 p. 3 - 19
反应条件
in water T=15°C; 105 h; pig liver esterase, further solvents, temperatures, enzymes; Product distribution;
参考文献
Rasor, Peter; Ruechardt, Christoph
Chemische Berichte, 1989 , vol. 122, p. 1375 - 1376
反应条件
Palomo reagent; triethylamine in toluene 48 h; Ambient temperature; Yields of byproduct given;
参考文献
Mazon, Angel; Najera, Carmen; Yus, Miguel; Heumann, Andreas
Tetrahedron: Asymmetry, 1992 , vol. 3, # 11 p. 1455 - 1466
反应条件
Palomo reagent; triethylamine in toluene 48 h; Ambient temperature; Yields of byproduct given;
参考文献
Mazon, Angel; Najera, Carmen; Yus, Miguel; Heumann, Andreas
Tetrahedron: Asymmetry, 1992 , vol. 3, # 11 p. 1455 - 1466
反应条件
dicyclohexyl-carbodiimide in toluene 6 h; Yields of byproduct given;
参考文献
Chinchilla; Najera; Yus; Heumann
Tetrahedron Asymmetry, 1991 , vol. 2, # 2 p. 101 - 104
反应条件
in toluene T=25°C; 16 h; Yield given. Yields of byproduct given;
参考文献
Gaertner, Holger; Salz, Ulrich; Ruechardt, Christoph
Angewandte Chemie, 1984 , vol. 96, # 2 p. 166 - 167