3-甲基-2(3H)-苯并噻唑酮合成路线 （共 74 条）
反应条件
1: ethanolic KOH-solution View Scheme
参考文献
Kiprianow; Pasenko
Zhurnal Obshchei Khimii, 1949 , vol. 19, p. 1521
Chem.Abstr., 1950 , p. 1097
反应条件
tetrabutylammomium bromide; dimethyl sulfate in sodium hydroxide; water; toluene
参考文献
Sumitomo Chemical Company, Limited
Patent: US4293702 A1, 1981 ;
反应条件
sodium hydroxide in water
参考文献
Adir et Compagnie
Patent: US5234924 A1, 1993 ;
US 5234924 A
反应条件
palladium diacetate; triethylamine; triphenylphosphine in tetrahydrofuran
T=100 - 110°C; P=20686.5 Torr; 60 h; Autoclave;
参考文献
Troisi, Luigino; Granito, Catia; Perrone, Serena; Rosato, Francesca
Tetrahedron Letters, 2011 , vol. 52, # 33 p. 4330 - 4332
反应条件
tetrabutylammomium bromide in chloroform
参考文献
Sumitomo Chemical Company, Limited
Patent: US4293702 A1, 1981 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=125°C; 2 h;
参考文献
Ucar, Huseyin; Van Derpoorten, Kim; Cacciaguerra, Silvia; Spampinato, Santi; Stables, James P.; Depovere, Paul; Isa, Majed; Masereel, Bernard; Delarge, Jacques; Poupaert, Jacques H.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 7 p. 1138 - 1145
反应条件
methanol; 1,4-dithio-DL-threitol
pH=7.2;
参考文献
MEDAREX, INC.
Patent: WO2005/112919 A2, 2005 ;
Location in patent: Page/Page column 153 ;
反应条件
potassium carbonate in butanone
Heating;
参考文献
Mellor, Michael; Osbourn, Susan E.
Tetrahedron, 1991 , vol. 47, # 12-13 p. 2255 - 2262
反应条件
in chloroform-d1
T=25°C; 24 h;
参考文献
Schroll, Alayne L.; Barany, George
Journal of Organic Chemistry, 1986 , vol. 51, # 10 p. 1866 - 1881
反应条件
1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in dimethyl sulfoxide
T=25°C; 0.333333 h;
参考文献
Nicolaou; Mathison, Casey J. N.; Montagnon, Tamsyn
Journal of the American Chemical Society, 2004 , vol. 126, # 16 p. 5192 - 5201
