(±)-4-氯苯乙烯环氧化物合成路线 （共 77 条）
反应条件
(S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc in water T=0°C;
参考文献
Capriati, Vito; Florio, Saverio; Luisi, Renzo; Salomone, Antonio
Organic Letters, 2002 , vol. 4, # 14 p. 2445 - 2448
反应条件
(S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc; water in tetrahydrofuran T=0 - 20°C; 48 h;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
反应条件
C64H74Cl2Co2N4O4; bis(triphenylphosphoranylidene)-ammonium acetate in toluene T=0°C; 3.5 h; Product distribution / selectivity;
参考文献
CORNELL RESEARCH FOUNDATION, INC.
Patent: WO2009/26261 A2, 2009 ;
Location in patent: Page/Page column 69; 76-77 ;
反应条件
Aspergillus niger CGMCC 0496 in phosphate buffer; N,N-dimethyl-formamide T=25°C; pH=8.0; 1 h; Title compound not separated from byproducts.;
参考文献
Jin, Hao; Li, Zu-Yi; Dong, Xiao-Wei
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 3 p. 408 - 414
反应条件
sodium azide; beta-hydroxyethylmercaptan; halohydrin dehalogenase from Agrobacterium radiobacter AD1 in water T=22°C; pH=7.3; Kinetics;
参考文献
Spelberg, Jeffrey H. Lutje; Van Vlieg, Johan E. T. Hylckama; Tang, Lixia; Janssen, Dick B.; Kellogg, Richard M.
Organic Letters, 2001 , vol. 3, # 1 p. 41 - 43
反应条件
water in hexane T=30°C; pH=7.5; 8 h; Enzymatic reaction; Catalytic behavior; enantioselective reaction;
参考文献
Wu, Shuke; Li, Aitao; Chin, Yit Siang; Li, Zhi
ACS Catalysis, 2013 , vol. 3, # 4 p. 752 - 759
反应条件
Agrobacterium radiobacter AD1 halohydrin dehalogenase W249F; sodium nitrite in dimethyl sulfoxide pH=7.5; Product distribution; Further Variations:Reagents;
参考文献
Hasnaoui, Ghannia; Lutje Spelberg, Jeffrey H.; De Vries, Erik; Tang, Lixia; Hauer, Bernhard; Janssen, Dick B.
Tetrahedron Asymmetry, 2005 , vol. 16, # 9 p. 1685 - 1692
反应条件
(S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc; water in tetrahydrofuran T=0 - 20°C; 48 h;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
反应条件
1: 4-chlorostyrene oxide With water; (S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc in tetrahydrofuran T=0 - 20°C; 16 h; 2: N-Boc-2-nitrobenzenesulfonamide With oxygen in tetrahydrofuran T=20°C; 72 h; Title compound not separated from byproducts;
参考文献
Kim, Sang Kyun; Jacobsen, Eric N.
Angewandte Chemie - International Edition, 2004 , vol. 43, # 30 p. 3952 - 3954
反应条件
(S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc; water in tetrahydrofuran T=0 - 20°C; 48 h;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
