3-(2-甲酰基苯基)丙酸合成路线 （共 6 条）
反应条件
ozone in dichloromethane T=-60°C;
参考文献
Chen, Qingqi; Lightner, David A.
Journal of Organic Chemistry, 1998 , vol. 63, # 8 p. 2665 - 2675
反应条件
sodium hypophosphite; nickel in pyridine; acetic acid
参考文献
Collet,A.; Jacques,J.
Chimica Therapeutica, 1970 , vol. 5, p. 163 - 168
反应条件
1: H2 / Pd-C / methanol 2: aq. NaH2PO2 / Raney-Ni / aq. acetic acid; pyridine View Scheme
参考文献
Collet,A.; Jacques,J.
Chimica Therapeutica, 1970 , vol. 5, p. 163 - 168
反应条件
1: aq. NaOH, TsCl 2: H2 / Pd-C / methanol 3: aq. NaH2PO2 / Raney-Ni / aq. acetic acid; pyridine View Scheme
参考文献
Collet,A.; Jacques,J.
Chimica Therapeutica, 1970 , vol. 5, p. 163 - 168
反应条件
1: 98 percent / lithium diisopropylamide / -70 °C 2: 79 percent / O3 / CH2Cl2 / -60 °C View Scheme
参考文献
Belmessieri, Dorine; Morrill, Louis C.; Simal, Carmen; Slawin, Alexandra M. Z.; Smith, Andrew D.
Journal of the American Chemical Society, 2011 , vol. 133, # 8 p. 2714 - 2720
反应条件
2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; AZADO; tetrabutylammomium bromide in water; acetonitrile T=0 - 20°C; 4 h; Inert atmosphere;
参考文献
Shibuya, Masatoshi; Shibuta, Takuro; Fukuda, Hayato; Iwabuchi, Yoshiharu
Organic Letters, 2012 , vol. 14, # 19 p. 5010 - 5013
