C21H15ClN2O2Pd; potassium carbonate in water T=50°C; Suzuki-Miyaura Coupling; 0.416667 h;

1: 1-bromo-4-(1,1-dimethylethyl)benzene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: With tri-isopropoxy-borane in tetrahydrofuran; hexane T=20°C; 2 h; 3: 1-bromo-4-nitro-benzene With barium dihydroxide; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; ethylene glycol dimethyl ether; hexane T=80°C;

1.1: t-BuLi / pentane; diethyl ether / -78 °C 1.2: pentane; diethyl ether / -100 - 20 °C 2.1: Ba(OH)2*8H2O / Pd(PPh3)4 / 1,2-dimethoxy-ethane / Heating View Scheme

palladium diacetate; silver trifluoroacetate; trifluoroacetic acid in 2,2,2-trifluoroethanol T=140°C; 15 h; Autoclave;

barium dihydroxide; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether Substitution; Suzuki reaction; Heating;

tin(ll) chloride in ethanol; ethyl acetate Heating;