1-Boc-5-(羟基甲基)-1H-吲哚合成路线 (共 5 条)
反应条件
triethylamine tris(hydrogen fluoride) in acetonitrile T=23°C; 20 h;
参考文献
MERCK and CO., INC.
Patent: WO2006/86255 A2, 2006 ;
Location in patent: Page/Page column 67 ;
WO 2006/086255 A2
反应条件
sodium tris(acetoxy)borohydride in 1,2-dichloro-ethane T=20°C; 8 h;
参考文献
Gilligan, Paul J.
Patent: US2006/63799 A1, 2006 ;
Location in patent: Page/Page column 7 ;
反应条件
diisobutylaluminium hydride in tetrahydrofuran; methanol; water; toluene
参考文献
Syntex (U.S.A.) LLC
Patent: US6492394 B1, 2002 ;
US 6492394 B1
参考文献
MERCK and CO., INC.
Patent: WO2006/86255 A2, 2006 ;
Location in patent: Page/Page column 67-68 ;
WO 2006/086255 A2
反应条件
phosphorus tribromide in diethyl ether; dichloromethane
0.666667 h;
参考文献
PHARMACIA CORPORATION
Patent: WO2005/18557 A2, 2005 ;
Location in patent: Page/Page column 295 ;
WO 2005/018557 A2