N-boc-1H-吲哚-5-甲醛合成路线 （共 7 条）
反应条件
potassium tert-butylate T=0 - 20°C; 72 h;
参考文献
Gilligan, Paul J.
Patent: US2006/63799 A1, 2006 ;
Location in patent: Page/Page column 7 ;
参考文献
MERCK and CO., INC.
Patent: WO2006/86255 A2, 2006 ;
Location in patent: Page/Page column 67-68 ;
WO 2006/086255 A2
反应条件
1: With 4-(N,N-dimethlyamino)pyridine in tetrahydrofuran; toluene T=15 - 30°C; 0.5 h; 2: With water; diisobutylaluminium hydride in toluene T=15 - 45°C; 3 h;
参考文献
MERCK and CO. INC.
Patent: WO2004/87651 A2, 2004 ;
Location in patent: Page 8 ;
WO 2004/087651 A2
反应条件
diisobutylaluminium hydride in tetrahydrofuran; toluene T=15 - 18°C; 4 h;
参考文献
Payack, Joseph F.; Vazquez, Enrique; Matty, Louis; Kress, Michael H.; McNamara, James
Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 175 - 178
反应条件
1: DMAP / toluene; tetrahydrofuran / 0.5 h / 20 - 25 °C 2: DIBAL / toluene; tetrahydrofuran / 4 h / 15 - 18 °C View Scheme
参考文献
Payack, Joseph F.; Vazquez, Enrique; Matty, Louis; Kress, Michael H.; McNamara, James
Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 175 - 178
反应条件
1: DMAP / toluene; tetrahydrofuran / 0.5 h / 20 - 25 °C 2: DIBAL / toluene; tetrahydrofuran / 4 h / 15 - 18 °C View Scheme
参考文献
Payack, Joseph F.; Vazquez, Enrique; Matty, Louis; Kress, Michael H.; McNamara, James
Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 175 - 178
反应条件
sodium tris(acetoxy)borohydride in 1,2-dichloro-ethane T=20°C; 8 h;
参考文献
Gilligan, Paul J.
Patent: US2006/63799 A1, 2006 ;
Location in patent: Page/Page column 7 ;
