acetic acid 1.5 h; Heating;

1: 72 percent / pyridine / Ambient temperature 2: 58 percent / N,N-dimethyl-acetamide / 18 h / 37 °C 3: 1.) 30percent H2O2, CH3COOH, 2.) CH3ONa / 1.) r.t., overnight, 2.) methanol, reflux, 24 h 4: 90 percent / 10percent CH3COOOH / 1.5 h / Heating View Scheme

1: 58 percent / N,N-dimethyl-acetamide / 18 h / 37 °C 2: 1.) 30percent H2O2, CH3COOH, 2.) CH3ONa / 1.) r.t., overnight, 2.) methanol, reflux, 24 h 3: 90 percent / 10percent CH3COOOH / 1.5 h / Heating View Scheme

1: 1.) 30percent H2O2, CH3COOH, 2.) CH3ONa / 1.) r.t., overnight, 2.) methanol, reflux, 24 h 2: 90 percent / 10percent CH3COOOH / 1.5 h / Heating View Scheme