4-(1-1,2,4-三唑基)苯甲醛合成路线 （共 7 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=120°C; 12 h;
参考文献
Marrapu, Vijay K.; Chaturvedi, Vinita; Singh, Shubhra; Singh, Shyam; Sinha, Sudhir; Bhandari, Kalpana
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 4302 - 4310
反应条件
potassium carbonate in pyridine; methanol; dichloromethane; ethyl acetate; toluene
参考文献
Japat Ltd.
Patent: US5703106 A1, 1997 ;
反应条件
potassium carbonate in pyridine 18 h; Heating;
参考文献
Sircar; Duell; Bristol; Weishaar; Evans
Journal of Medicinal Chemistry, 1987 , vol. 30, # 6 p. 1023 - 1029
反应条件
pyridinium chlorochromate in dichloromethane 1.5 h; Ambient temperature;
参考文献
Artico; Silvestri; Stefancich; Avigliano; Di Giulio; Maccarrone; Agostinelli; Mondovi; Morpurgo
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 3 p. 219 - 228
反应条件
1: 48 percent / NaH / dimethylsulfoxide / 18 h / 100 °C 2: 77 percent / NaBH4, CaCl2 / tetrahydrofuran / Ambient temperature 3: 49 percent / pyridinium chlorochromate (PCC) / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Artico; Silvestri; Stefancich; Avigliano; Di Giulio; Maccarrone; Agostinelli; Mondovi; Morpurgo
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 3 p. 219 - 228
反应条件
1: 77 percent / NaBH4, CaCl2 / tetrahydrofuran / Ambient temperature 2: 49 percent / pyridinium chlorochromate (PCC) / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Artico; Silvestri; Stefancich; Avigliano; Di Giulio; Maccarrone; Agostinelli; Mondovi; Morpurgo
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 3 p. 219 - 228
反应条件
1: With silver nitrate; sodium hydroxide in water T=60°C; 24 h; 2: With hydrogenchloride in water pH=Ca. 2;
参考文献
Wang, Yu-Ling; Fu, Jiang-Hong; Wei, Jia-Jia; Xu, Xiang; Li, Xin-Fa; Liu, Qing-Yan
Crystal Growth and Design, 2012 , vol. 12, # 9 p. 4663 - 4668
