4-苄基-1-(三氟乙酰基)哌嗪合成路线 （共 8 条）
反应条件
potassium tert-butylate in tetrahydrofuran; N,N-dimethyl-formamide T=20°C; 24 h;
参考文献
Jablonski, Lukas; Joubert, Jerome; Billard, Thierry; Langlois, Bernard R.
Synlett, 2003 , # 2 p. 230 - 232
反应条件
potassium tert-butylate in tetrahydrofuran; N,N-dimethyl-formamide T=20°C; 24 h;
参考文献
Jablonski, Lukas; Joubert, Jerome; Billard, Thierry; Langlois, Bernard R.
Synlett, 2003 , # 2 p. 230 - 232
反应条件
potassium carbonate in methanol; water 20 h;
参考文献
Kawaguchi, Mamoru; Hayashi, Osamu; Kanamoto, Masahiro; Hamada, Masayuki; Yamamoto, Yukio; Oda, Jun'ichi
Agricultural and Biological Chemistry, 1987 , vol. 51, # 2 p. 435 - 440
参考文献
Am. Cyanamid Co.
Patent: US2909524 , 1958 ;
反应条件
triethylamine in dichloromethane
2 h;
参考文献
Miller, Michael W.; Vice, Susan F.; McCombie, Stuart W.
Tetrahedron Letters, 1998 , vol. 39, # 21 p. 3429 - 3432
反应条件
triethylamine in dichloromethane
2 h;
参考文献
Miller, Michael W.; Vice, Susan F.; McCombie, Stuart W.
Tetrahedron Letters, 1998 , vol. 39, # 21 p. 3429 - 3432
反应条件
sodium cyanoborohydride; ozone; acetic acid
1.)MeOH, CH2Cl2; -60 deg C; 2.) MeOH, -60 deg C, 10 min; 0 deg C for 20 h; Yield given. Multistep reaction;
参考文献
Kawaguchi, Mamoru; Hayashi, Osamu; Kanamoto, Masahiro; Hamada, Masayuki; Yamamoto, Yukio; Oda, Jun'ichi
Agricultural and Biological Chemistry, 1987 , vol. 51, # 2 p. 435 - 440
反应条件
1: 1 N NaOH / methanol
View Scheme
参考文献
Miller, Michael W.; Vice, Susan F.; McCombie, Stuart W.
Tetrahedron Letters, 1998 , vol. 39, # 21 p. 3429 - 3432
