5-甲酰基-4-甲基-1H-吡咯-2-羧酸合成路线 （共 4 条）
反应条件
potassium hydroxide in ethanol Heating;
参考文献
Sugen, Inc.
Patent: US2004/266843 A1, 2004 ;
Location in patent: Page 16; 17 ;
反应条件
1: 68 percent / POCl3 / Heating 2: 68 percent / aq. KOH / ethanol / Heating View Scheme
参考文献
Sun; Cui, Jean; Liang, Congxin; Zhou, Yong; Nematalla, Asaad; Wang, Xueyan; Chen, Hui; Tang, Cho; Wei, James
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 16 p. 2153 - 2157
反应条件
benzotriazol-1-ol; triethylamine in N,N-dimethyl-formamide
参考文献
Liang, Congxin; Sun, Li; Wei, Chung Chen; Tang, Peng Cho; McMahon, Gerald; Hirth, Klaus Peter; Cui, Jingrong
Patent: US2002/183319 A1, 2002 ;
US 20020183319 A1
反应条件
benzotriazol-1-ol; N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine in N,N-dimethyl-formamide T=20°C;
参考文献
Sun; Cui, Jean; Liang, Congxin; Zhou, Yong; Nematalla, Asaad; Wang, Xueyan; Chen, Hui; Tang, Cho; Wei, James
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 16 p. 2153 - 2157
