bis-triphenylphosphine-palladium(II) chloride in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=80°C; 1 h;

1.1: N,N-dicyclohexylamine / triphenylphosphine; palladium diacetate / toluene / 0.42 h / 20 °C / Industry scale; Inert atmosphere 1.2: 18.4 - 22.3 °C / Industry scale; Inert atmosphere 2.1: sodium methylate / toluene; methanol / 4 h / 40 - 50 °C / Industry scale 2.2: 16 h / Industry scale 3.1: acetic acid / toluene / 950 h / 10 - 33 °C / Industry scale 4.1: chloranil / tetrahydrofuran / 22 h / 60 - 70 °C / Industry scale View Scheme

aluminium trichloride 0.0833333 h; Ambient temperature;

bis-triphenylphosphine-palladium(II) chloride in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=80°C; 1 h;