2-噻吩羧酸乙酯合成路线

参考文献

Mloston, Grzegorz; Urbaniak, Katarzyna; Jacaszek, Natalia; Linden, Anthony; Heimgartner, Heinz
Heterocycles, 2014 , vol. 88, # 1 p. 387 - 401

88-15-32-乙酰基噻吩+

2810-04-02-噻吩羧酸乙酯

1138-14-3

参考文献

Ishii, Akihiko; Nakayama, Juzo; Kazami, Jun-ichi; Ida, Yutaka; Nakamura, Takao; Hoshino, Masamatsu
Journal of Organic Chemistry, 1991 , vol. 56, # 1 p. 78 - 82

2810-04-02-噻吩羧酸乙酯+

100-97-0乌洛托品

67808-65-55-甲酰基噻吩-2-羧酸乙酯

参考文献

Ahmed, S. Kaleem; Etoga, Jean-Louis G.; Patel, Sarjubhai A.; Bridges, Richard J.; Thompson, Charles M.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4358 - 4362

2810-04-02-噻吩羧酸乙酯+

68-12-2N,N-二甲基甲酰胺

67808-65-55-甲酰基噻吩-2-羧酸乙酯

参考文献

ELI LILLY AND COMPANY
Patent: EP1856090 B1, 2009 ;
Location in patent: Page/Page column 49; 57 ;

2810-04-02-噻吩羧酸乙酯+

76-05-1三氟乙酸

67808-65-55-甲酰基噻吩-2-羧酸乙酯

参考文献

PRINCIPIA BIOPHARMA INC.; BRAMELD, Kenneth, A.; OWENS, Tim, A.
Patent: WO2014/36016 A1, 2014 ;
Location in patent: Page/Page column 170; 171 ;

2591-86-8哌啶-1-甲醛+

2810-04-02-噻吩羧酸乙酯

67808-65-55-甲酰基噻吩-2-羧酸乙酯

参考文献

Shilai, Manabu; Kondo, Yoshinori; Sakamoto, Takao
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 4 p. 442 - 444

2810-04-02-噻吩羧酸乙酯+

74497-02-2

6846-13-5

参考文献

Varma, Rajender S.; Naicker, Kannan P.
Tetrahedron Letters, 1999 , vol. 40, # 34 p. 6177 - 6180

2810-04-02-噻吩羧酸乙酯+

74-95-3二溴甲烷

68672-88-82,2-二溴-1-噻吩-2-乙酮

参考文献

Hartwig, Jan; Metternich, Jan B.; Nikbin, Nikzad; Kirschning, Andreas; Ley, Steven V.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 22 p. 3611 - 3615

参考文献

Malancona, Savina; Hernando, Jose I. Martin; Attenni, Barbara; Ontoria, Jesus M.; Narjes, Frank
Tetrahedron Letters, 2009 , vol. 50, # 14 p. 1625 - 1628

2810-04-02-噻吩羧酸乙酯+

107-15-3乙二胺

45753-18-24,5-二氢-2-(2-噻吩)-1H-咪唑

参考文献

Neef, Guenter; Eder, Ulrich; Sauer, Gerhard
Journal of Organic Chemistry, 1981 , vol. 46, # 13 p. 2824 - 2826