2-溴-6-(羟基甲基)苯酚合成路线 （共 5 条）
反应条件
1: With propionic acid; 3,4,5-trimethoxyphenylboronic acid in toluene 18 h; Heating; 2: With dihydrogen peroxide in tetrahydrofuran T=0°C; 0.75 h;
参考文献
Ducho; Jessel; Gisch; Balzarini; Meier
Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 5-7 p. 519 - 522
反应条件
1: With triethylamine; magnesium chloride in tetrahydrofuran T=70°C; 16 h; 2: With dihydrogen peroxide; sodium hydroxide in tetrahydrofuran T=20°C; Dakin oxidation; 16 h;
参考文献
Kobayashi, Yuichi; Lalitnorasate, Paveena; Kaneko, Yuki; Kiyotsuka, Yohei; Endo, Yoshiki
Tetrahedron Letters, 2010 , vol. 51, # 46 p. 6018 - 6021
反应条件
sodium tetrahydroborate in methanol T=0°C;
参考文献
Yoshimura, Tomoyuki; Tomohara, Keisuke; Kawabata, Takeo
Journal of the American Chemical Society, 2013 , vol. 135, # 19 p. 7102 - 7105
反应条件
1.1: magnesium chloride; triethylamine / acetonitrile / 0.25 h / 20 °C 1.2: 3 h / |Reflux 2.1: sodium tetrahydroborate / methanol / 0 °C View Scheme
参考文献
Yoshimura, Tomoyuki; Tomohara, Keisuke; Kawabata, Takeo
Journal of the American Chemical Society, 2013 , vol. 135, # 19 p. 7102 - 7105
反应条件
toluene-4-sulfonic acid; sodium sulfate in acetone
T=40°C; 72 h;
参考文献
Ducho; Jessel; Gisch; Balzarini; Meier
Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 5-7 p. 519 - 522
