3,5-二硝基-2-甲基苯甲酸合成路线 (共 23 条)
反应条件
1: 3,5-dinitro-2-methyl benzoic acid With thionyl chloride
4 h; Reflux;
2: ethanol in dichloromethane
T=20°C; 1 h;
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US2012/309758 A1, 2012 ;
Location in patent: Page/Page column 73 ;
US 20120309758 A1
反应条件
in thionyl chloride; ethanol; dichloromethane
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;
Title/Abstract Full Text Show Details
Vertex Pharmaceuticals Incorporated
Patent: US2012/309758 A1, 2012 ;
US 20120309758 A1
反应条件
thionyl chloride
Substitution;
参考文献
Spanggord, Ronald J.; Clizbe, Lane A.
Journal of Labelled Compounds and Radiopharmaceuticals, 1998 , vol. 41, # 7 p. 615 - 621