1-氰基环丁基羧酸乙酯合成路线

参考文献

TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2009/67547 A1, 2009 ;
Location in patent: Page/Page column 281-282 ;
WO 2009/067547 A1

2999-46-4异氰基乙酸乙酯+

109-64-81,3-二溴丙烷

28246-87-91-氰基环丁基羧酸乙酯

参考文献

Kalvin, Douglas; Ramalingam, Kondareddiar; Woodward, Ronald
Synthetic Communications, 1985 , vol. 15, # 4 p. 267 - 272

105-56-6氰乙酸乙酯+

109-64-81,3-二溴丙烷

参考文献

Zefirov, N. S.; Kuznetsova, T. S.; Kozhushkov, S. I.; Surmina, L. S.; Rashchupkina, Z. A.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, p. 474 - 480
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 3 p. 541 - 548

105-56-6氰乙酸乙酯

28246-87-91-氰基环丁基羧酸乙酯

参考文献

Gosselck,J.; Winkler,A.
Tetrahedron Letters, 1970 , p. 2437 - 2440

28246-87-91-氰基环丁基羧酸乙酯

141-82-2丙二酸+

5445-51-21,1-环丁基二甲酸

参考文献

Journal of the Chemical Society, , p. 144

28246-87-91-氰基环丁基羧酸乙酯

3721-95-7环丁基甲酸

参考文献

Sugden; Wilkins
Journal of the Chemical Society, 1927 , p. 144

28246-87-91-氰基环丁基羧酸乙酯

911060-83-81-(氨基甲基)-环丁烷羧酸乙酯

参考文献

TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2009/67547 A1, 2009 ;
Location in patent: Page/Page column 281; 282 ;
WO 2009/067547 A1

28246-87-91-氰基环丁基羧酸乙酯

141-82-2丙二酸+

5445-51-21,1-环丁基二甲酸

参考文献

Sugden; Wilkins
Journal of the Chemical Society, 1927 , p. 144

28246-87-91-氰基环丁基羧酸乙酯

30491-91-91-氰基环丁烷羧酸

参考文献

Hall,H.K. et al.
Journal of the American Chemical Society, 1971 , vol. 93, # 1 p. 110 - 120

28246-87-91-氰基环丁基羧酸乙酯

845621-11-61-氨基羰基环丁烷羧酸

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: WO2005/19158 A1, 2005 ;
Location in patent: Page/Page column 17-18 ;