(E)-2-甲基-3-(2-硝基乙烯基)-1H-吲哚合成路线 （共 7 条）
反应条件
ammonium acetate 3 h; Reflux;
参考文献
Balamurugan, Ramalingam; Sureshbabu, Radhakrishnan; Rajeshwaran, Ganesan Gobi; Mohanakrishnan, Arasambattu K.
Synthetic Communications, 2009 , vol. 39, # 3 p. 531 - 543
反应条件
trifluoroacetic acid in dichloromethane 1.) 0 deg C, 1 h, 2.) r.t., 5 h;
参考文献
Mahboobi; Grothus; Meindl
Archiv der Pharmazie, 1994 , vol. 327, # 2 p. 105 - 114
反应条件
trifluoroacetic acid in dichloromethane 1) 0 deg C, 2.5 h, 2) rt, 20 h;
参考文献
Freund, Ralf; Mahboobi, Siavosh; Noack, Klaus; Schoenholzer, Peter; Bernauer, Karl
Helvetica Chimica Acta, 1990 , vol. 73, p. 439 - 454
反应条件
1: 1.) 2,3-dichloro-5,6-dicyan-p-benzoquinone; 2.) potassium carbonate / 1.) tetrahydrofuran, water, room temperature, 10 h; 2.) 1 h 2: 65 percent / ammonium acetate / 2 h / 120 - 130 °C View Scheme
参考文献
Canoira; Gonzalo Rodriguez; Subirats; Escario; Jimenez; Martinez-Fernandez
European Journal of Medicinal Chemistry, 1989 , vol. 24, # 1 p. 39 - 42
反应条件
1: POCl3 2: AcOH View Scheme
参考文献
Harada, Hiroshi; Hirokawa, Yoshimi; Suzuki, Kenji; Hiyama, Yoichi; Oue, Mayumi; Kawashima, Hitoshi; Yoshida, Naoyuki; Furutani, Yasuji; Kato, Shiro
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 7 p. 1301 - 1305
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 7 p. 1301 - 1305
反应条件
1: sodium tris(acetoxy)borohydride / tetrahydrofuran
2: palladium 10 on activated carbon; ammonium formate / methanol
3: triethylamine / tetrahydrofuran / 0.5 h / 20 °C
View Scheme
参考文献
Baggett, Andrew W.; Cournia, Zoe; Han, Min Suk; Patargias, George; Glass, Adam C.; Liu, Shih-Yuan; Nolen, Brad J.
ChemMedChem, 2012 , vol. 7, # 7 p. 1286 - 1294
