N-Fmoc-3-碘-l-丙氨酸叔丁酯合成路线 （共 6 条）
反应条件
1H-imidazole in dichloromethane Iodination; 0.5 h; Heating;
参考文献
Organic letters, , vol. 2, # 15 p. 2265 - 2267
反应条件
sodium iodide in acetone 72 h; Heating;
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 16 p. 1876 - 1884
反应条件
1.1: dicyclohexylcarbodiimide; copper(I) chloride / 72 h / 20 °C 1.2: 67 percent / CH2Cl2 / 2 h / 20 °C 2.1: 88 percent / methyltriphenoxyphosphonium iodide / dimethylformamide / 1 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 7 p. 2200 - 2209
反应条件
1: 78 percent / aq. NaHCO3 / acetone / 48 h / 20 °C 2: 84 percent / H2SO4 / CH2Cl2 / 19 h / 20 °C 3: 99 percent / NaI / acetone / 72 h / Heating View Scheme
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 16 p. 1876 - 1884
反应条件
1: 84 percent / H2SO4 / CH2Cl2 / 19 h / 20 °C 2: 99 percent / NaI / acetone / 72 h / Heating View Scheme
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 16 p. 1876 - 1884
反应条件
1.1: Zn; Me3SiCl / dimethylformamide / 20 °C 1.2: 34 percent / P(o-tol)3 / tris(dibenzylideneacetone)dipalladium / dimethylformamide / 4 h / 50 °C 2.1: 64 percent / Et3SiH; TFA / CH2Cl2 / 4 h / 20 °C View Scheme
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 16 p. 1876 - 1884
