beta-(氨基甲基)-4-甲基-苯丙酸盐酸盐合成路线 （共 2 条）
反应条件
hydrogenchloride; water in water
16 h; Reflux;
参考文献
Biswas, Kallolmay; Gholap, Rajesh; Srinivas, Padakanti; Kanyal, Sachin; Sarma, Koushik Das
RSC Advances, 2014 , vol. 4, # 5 p. 2538 - 2545
反应条件
1.1: cesium fluoride; tetrabutyl-ammonium chloride; bis-triphenylphosphine-palladium(II) chloride / toluene; water / 18 h / 20 °C / |Inert atmosphere
2.1: acetic acid / chloroform / 1 h / 0 - 20 °C
2.2: 20 °C
3.1: trifluoroacetic acid / 1,2-dichloro-ethane / 2 h / 80 °C
4.1: nickel dichloride; sodium tetrahydroborate / methanol; tetrahydrofuran / 1 h / 0 - 20 °C
5.1: hydrogenchloride; water / water / 16 h / |Reflux
View Scheme
参考文献
Biswas, Kallolmay; Gholap, Rajesh; Srinivas, Padakanti; Kanyal, Sachin; Sarma, Koushik Das
RSC Advances, 2014 , vol. 4, # 5 p. 2538 - 2545
