1-乙酰基-4-BOC氨基哌啶合成路线 (共 2 条)
反应条件
triethylamine in dichloromethane T=0 - 20°C; 18 h;
参考文献
Arete Therapeutics, Inc.
Patent: US2008/227780 A1, 2008 ;
Location in patent: Page/Page column 53-54 ;
US 20080227780 A1
反应条件
1: With hydrogenchloride in 1,4-dioxane; methanol T=20°C; 18 h; 2: With sodium hydroxide in water pH=< 10; Product distribution / selectivity;
参考文献
Arete Therapeutics, Inc.
Patent: US2008/227780 A1, 2008 ;
Location in patent: Page/Page column 53-54 ;
US 20080227780 A1