5-乙氧基-2(5H)-呋喃酮合成路线 （共 36 条）
反应条件
water 1) THF, -70 deg C, 2) -20 deg C; Yield given. Multistep reaction;
参考文献
Machado-Araujo, Francisca W. L.; Gore, Jacques
Tetrahedron, 1982 , vol. 38, # 19 p. 2897 - 2904
反应条件
sulfuric acid; sodium hydrogensulfite 1,) reflux, 1 d, 2.) 90 deg C, 6 h; Yield given. Multistep reaction;
参考文献
Landor, Stephen R.; Landor, Phyllis, D.; Kalli, Michael
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2921 - 2926
反应条件
sulfuric acid 24 h; Heating; Title compound not separated from byproducts;
参考文献
Landor, Stephen R.; Landor, Phyllis, D.; Kalli, Michael
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2921 - 2926
反应条件
trimethyl-oxo-sulfonium iodide; sodium hydride
参考文献
Landor, Stephen R.; Landor, Phyllis, D.; Kalli, Michael
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2921 - 2926
反应条件
sodium hydride Multistep reaction;
参考文献
Landor, Stephen R.; Landor, Phyllis, D.; Kalli, Michael
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2921 - 2926
反应条件
bromine in tetrachloromethane T=0 - 20°C; 3.5 h;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED?
Patent: WO2005/90334 A2, 2005 ;
Location in patent: Page/Page column 66-67 ;
WO 2005/090334 A2
反应条件
bromine in tetrachloromethane
参考文献
Wannamaker, Marion W.; Forster, Cornelia
Patent: US2003/119899 A1, 2003 ;
反应条件
trimethyl-oxo-sulfonium iodide; sodium hydride
参考文献
Landor, Stephen R.; Landor, Phyllis, D.; Kalli, Michael
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2921 - 2926
反应条件
sodium hydride Multistep reaction;
参考文献
Landor, Stephen R.; Landor, Phyllis, D.; Kalli, Michael
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2921 - 2926
反应条件
hydrogenchloride T=80°C; 0.0833333 h; var. acylamides; Product distribution;
参考文献
Valla, Alain; Giraud, Michel; Labia, Roger; Morand, Annick
Bulletin de la Societe Chimique de France, 1997 , vol. 134, # 6 p. 601 - 604
