反应条件
1.1: 99 percent / Et3N / CH2Cl2 / 0.33 h / 0 °C
2.1: O3 / CH2Cl2 / 0.5 h / -78 °C
2.2: DMS / CH2Cl2 / 1 h / 20 °C
2.3: 45 percent / aq. HCl / ethanol / 1 h / Heating
3.1: 87 percent / K2CO3 / dimethylformamide / 2 h / 20 °C
4.1: 91 percent / NaHSO3; aq. H2O2; NaClO2 / acetonitrile / 6 h / 10 °C
5.1: (COCl)2; DMF / CH2Cl2 / 1.5 h / Heating
6.1: 293 mg / Et3N / CH2Cl2 / 0.5 h / 20 °C
7.1: 81 percent / Bu3P; 1,3-bis-(diphenylphosphino)propane; iPr2NEt / Pd(OAc)2 / dimethylformamide / 0.5 h / Heating
View Scheme
参考文献
Harayama, Takashi; Akiyama, Toshihiko; Nakano, Yuichiro; Shibaike, Kentaro; Akamatsu, Hisashi; Hori, Akihiro; Abe, Hitoshi; Takeuchi, Yasuo
Synthesis, 2002 , # 2 p. 237 - 241
