反应条件
1: CH2Cl2 2: aq. NH3 / ethanol 3: 60 percent / Cs2CO3 / dimethylformamide 4: 1.) KOt-Bu, 2.) 2,4,6-trimethylbenzenesulfonyl azide / 1.) THF, -78 deg C, 2.) THF, -78 deg C 5: PPh3 / tetrahydrofuran; H2O View Scheme
参考文献
Selnick, Harold G.; Liverton, Nigel J.; Baldwin, John J.; Butcher, John W.; Claremon, David A.; Elliott, Jason M.; Freidinger, Roger M.; King, Stella A.; Libby, Brian E.; McIntyre, Charles J.; Pribush, David A.; Remy, David C.; Smith, Garry R.; Tebben, Andrew J.; Jurkiewicz, Nancy K.; Lynch, Joseph J.; Salata, Joseph J.; Sanguinetti, Michael C.; Siegl, Peter K.S.; Slaughter, Donald E.; Vyas, Kamlesh
Journal of Medicinal Chemistry, 1997 , vol. 40, # 24 p. 3865 - 3868
