4-(3-氧环戊基)苯甲腈合成路线 （共 2 条）
反应条件
1: para-iodobenzonitrile With iso-propylmagnesium bromide in tetrahydrofuran
T=-40°C; Metallation; 1 h;
2: cyclopent-2-enone With N,N,N',N',N'',N''-hexamethylphosphoric triamide; chloro-trimethyl-silane; copper(I) bromide dimethylsulfide complex in tetrahydrofuran
Conjugate addition; 1 h;
参考文献
Varchi, Greta; Ricci, Alfredo; Cahiez, Gerard; Knochel, Paul
Tetrahedron, 2000 , vol. 56, # 18 p. 2727 - 2731
反应条件
sodium acetate; acetic acid; palladium diacetate; antimony trichloride
T=25°C; 24 h;
参考文献
UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Patent: WO2007/98474 A1, 2007 ;
Location in patent: Page/Page column 27 ;
WO 2007/098474 A1
