16,17-环氧-21-乙酰氧基孕烯醇酮合成路线 （共 3 条）
反应条件
1: 84 percent / 24 h / 20 - 25 °C 2: 92 percent / acetylacetone / aq. acetic acid / 1 h / 85 - 95 °C 3: 90 percent / 57percent HClO4 / methanol / 6 h / 40 - 42 °C 4: 39.4 percent / pyridine / 20 h / -10 °C View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 17, # 2 p. 144 - 147
Khimiko-Farmatsevticheskii Zhurnal, , vol. 17, # 2 p. 200 - 203
反应条件
1: 84 percent / 24 h / 20 - 25 °C 2: 92 percent / acetylacetone / aq. acetic acid / 1 h / 85 - 95 °C 3: 90 percent / 57percent HClO4 / methanol / 6 h / 40 - 42 °C View Scheme
参考文献
Krymov, A. P.; Kamernitskii, A. V.; Demchenko, B. I.; Vesela, I. V.; Tropina, V. I.; Ioanis'yan, L. I.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 2 p. 144 - 147
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 2 p. 200 - 203
反应条件
cyclohexanone; aluminum isopropoxide; toluene
参考文献
Julian et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 5145
