4-(4-氨基苯氧基)-N-甲基-2-吡啶甲酰胺合成路线 （共 22 条）
反应条件
1: 4-Chloro-3-(trifluoromethyl)benzenamine; 1,1'-carbonyldiimidazole in dichloromethane T=20°C; 16 h; Inert atmosphere; 2: 4-(4-aminophenoxy)pyridine-2-carboxylic acid methylamide in dichloromethane Inert atmosphere;
参考文献
Bankston, Donald; Dumas, Jacques; Natero, Reina; Riedl, Bernd; Monahan, Mary-Katherine; Sibley, Robert
Organic Process Research and Development, 2002 , vol. 6, # 6 p. 777 - 781
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide 24 h; Heating / reflux; Product distribution / selectivity;
参考文献
CIPLA LIMITED
Patent: US2010/311980 A1, 2010 ;
Location in patent: Page/Page column 24 ;
