4-(3-氨基苯氧基)-N-甲基-2-吡啶羧胺合成路线 （共 6 条）
反应条件
hydrogen; nickel in tetrahydrofuran; methanol T=20°C;
参考文献
MERCK PATENT GMBH
Patent: WO2005/5389 A2, 2005 ;
Location in patent: Page 171 ;
WO 2005/005389 A2
反应条件
potassium tert-butylate; potassium carbonate in N,N-dimethyl-formamide T=20 - 90°C; 1 h; Inert atmosphere;
参考文献
Yao, Jianwen; He, Zuopeng; Chen, Jing; Sun, Wei; Fang, Hao; Xu, Wenfang
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6549 - 6553,5
反应条件
1: thionyl chloride 2: tetrahydrofuran 3: potassium tert-butylate; potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 - 90 °C / |Inert atmosphere View Scheme
参考文献
Yao, Jianwen; He, Zuopeng; Chen, Jing; Sun, Wei; Fang, Hao; Xu, Wenfang
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6549 - 6553,5
反应条件
1: tetrahydrofuran 2: potassium tert-butylate; potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 - 90 °C / |Inert atmosphere View Scheme
参考文献
Yao, Jianwen; He, Zuopeng; Chen, Jing; Sun, Wei; Fang, Hao; Xu, Wenfang
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6549 - 6553,5
参考文献
Riedl, Bernd; Dumas, Jacques; Khire, Uday; Lowinger, Timothy B.; Scott, William J.; Smith, Roger A.; Wood, Jill E.; Monahan, Mary-Katherine; Natero, Reina; Renick, Joel; Sibley, Robert N.
Patent: US2001/11135 A1, 2001 ;
US 20010011135 A1
Title/Abstract Full Text Show Details
BAYER CORPORATION
Patent: US2002/165394 A1, 2002 ;
US 20020165394 A1
Title/Abstract Full Text Show Details
BAYER CORPORATION
Patent: US2003/181442 A1, 2003 ;
参考文献
US2003/144278 A1, ;
US 20030144278 A1
