3,4-二氢-3,3-二甲基-异喹啉合成路线 （共 11 条）
反应条件
sodium tungstate; dihydrogen peroxide in ethanol
参考文献
Bernotas, Ronald C.; Thomas, Craig E.; Carr, Albert A.; Nieduzak, Thaddeus R.; Adams, Ginette; Ohlweiler, David F.; Hay, David A.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 10 p. 1105 - 1110
反应条件
lithium aluminium tetrahydride in diethyl ether 1 h; Heating;
参考文献
Mikhailovskii, A. G.; Aleksandrov, B. B.; Vakhrin, M. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1993 , vol. 29, # 6 p. 668 - 670
Khimiya Geterotsiklicheskikh Soedinenii, 1993 , # 6 p. 780 - 783
反应条件
potassium hydroxide in methanol
17 h; Heating;
参考文献
Watson
Journal of Organic Chemistry, 1998 , vol. 63, # 2 p. 406 - 407
反应条件
1: With oxalyl dichloride in dichloromethane
2: With anhydrous iron chloride
3: With methanol; sulfuric acid
参考文献
Kammoun, Majed; Salah, Hassen Ben; Damak, Mohamed
Synthetic Communications, 2011 , vol. 41, # 10 p. 1520 - 1528
反应条件
manganese(IV) oxide in hexane
Heatingother reagent;
参考文献
Sokol, V. L.; Ryabov, M. A.; Merkur'eva, N. Yu.; Davydov, V. V.; Shklyaev, Yu. V.; et al.
Russian Chemical Bulletin, 1995 , vol. 44, # 12 p. 2364 - 2370
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 1995 , # 12 p. 2468 - 2474
反应条件
naphthalene; sodium in various solvent(s)
参考文献
Watson
Journal of Organic Chemistry, 1998 , vol. 63, # 2 p. 406 - 407
反应条件
1: 99 percent / triethylamine / CH2Cl2 / 12 h / Ambient temperature
2: 99 percent / boron trifluoride diethyl etherate / 12 h / Ambient temperature
3: 90 percent / KOH / methanol / 17 h / Heating
View Scheme
参考文献
Watson
Journal of Organic Chemistry, 1998 , vol. 63, # 2 p. 406 - 407
反应条件
1: 99 percent / boron trifluoride diethyl etherate / 12 h / Ambient temperature
2: 90 percent / KOH / methanol / 17 h / Heating
View Scheme
参考文献
Watson
Journal of Organic Chemistry, 1998 , vol. 63, # 2 p. 406 - 407
反应条件
1: 73 percent / H2SO4 / acetic acid
2: 13 percent / polyphosphoric acid
View Scheme
参考文献
Bernotas, Ronald C.; Thomas, Craig E.; Carr, Albert A.; Nieduzak, Thaddeus R.; Adams, Ginette; Ohlweiler, David F.; Hay, David A.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 10 p. 1105 - 1110
反应条件
1: With sulfuric acid; acetic acid
T=20°C;
2: With oxalyl dichloride in dichloromethane
3: With anhydrous iron chloride; sulfuric acid in methanol
参考文献
Ben Saleh, Hassen; Kammoun, Majed; Hamdi, Besma; Damak, Mohamed
Synthetic Communications, 2012 , vol. 42, # 22 p. 3296 - 3303
