3-氨基-4-(异丙基氨基)苯甲酸合成路线 （共 2 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate T=20°C; P=760 Torr; 3 h;
参考文献
ARENA PHARMACEUTICALS, INC.
Patent: WO2004/41274 A1, 2004 ;
Location in patent: Page/Page column 47 ;
WO 2004/041274 A1
反应条件
1: aq. NaHCO3 / 0.33 h / 150 °C / microwave irradiation 2: H2 / Pd/C / ethyl acetate / 3 h / 20 °C / 760 Torr View Scheme
参考文献
Semple, Graeme; Skinner, Philip J.; Cherrier, Martin C.; Webb, Peter J.; Sage, Carleton R.; Tamura, Susan Y.; Chen, Ruoping; Richman, Jeremy G.; Connolly, Daniel T.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 4 p. 1227 - 1230
