1-甲基-4-硝基-1H-吡咯-2-碳酰肼合成路线 （共 4 条）
反应条件
hydrazine hydrate in tetrahydrofuran; water T=0°C;
参考文献
Jing-Lin, Wang; Bin, Liu; Bin-Sheng, Yang
CrystEngComm, 2011 , vol. 13, # 23 p. 7086 - 7097
反应条件
hydrazine hydrate in ethanol 0.25 h;
参考文献
Firoozi; Javidnia; Kamali; Fooladi; Foroumadi; Shafiee
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 1 p. 123 - 128
反应条件
1: nitric acid / acetic anhydride / 4 h / -10 - 20 °C / |Inert atmosphere 2: hydrazine hydrate / ethanol / 1 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Rane, Rajesh A.; Bangalore, Pavankumar; Borhade, Sheetal D.; Khandare, Preeti K.
European Journal of Medicinal Chemistry, 2013 , vol. 70, p. 49 - 58
反应条件
1: potassium carbonate / diethyl ether / |Inert atmosphere 2: nitric acid / acetic anhydride / 4 h / -10 - 20 °C / |Inert atmosphere 3: hydrazine hydrate / ethanol / 1 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Rane, Rajesh A.; Bangalore, Pavankumar; Borhade, Sheetal D.; Khandare, Preeti K.
European Journal of Medicinal Chemistry, 2013 , vol. 70, p. 49 - 58
