反应条件
1: 1.) bis(trimethylsilyl)acetamide / 1.) dichloroethane, reflux, 1 h, 2.) dichloroethane, acetonitrile, RT, 18 h
2: NH3 / methanol / 24 h / Ambient temperature
View Scheme
参考文献
Orr; Musso; Boswell; Kelley; Joyner; Davis; Baccanari
Journal of Medicinal Chemistry, 1995 , vol. 38, # 19 p. 3850 - 3856
