N,N-二甲基-1H-苯并咪唑-2-胺合成路线 （共 9 条）
反应条件
dimethyl amine in water; N,N-dimethyl-formamide
参考文献
Kyowa Hakko Kirin Co., Ltd.; YAMAMOTO, Keisuke; TAMURA, Tomohiro; NAKAMURA, Rina; UENO, Kimihisa; HOSOE, Shintaro
Patent: EP2740730 A1, 2014 ;
Location in patent: Page/Page column ;
反应条件
copper(l) iodide; caesium carbonate; N-methyl-2-(methylamino)ethylamine in N,N-dimethyl acetamide T=130°C; 16 h; Inert atmosphere;
参考文献
Deng, Xiaohu; McAllister, Heather; Mani, Neelakandha S.
Journal of Organic Chemistry, 2009 , vol. 74, # 15 p. 5742 - 5745
反应条件
ammonia in water T=240°C; 0.5 h;
参考文献
Petersen, Trine P.; Larsen, Anders Foller; Ritzen, Andreas; Ulven, Trond
Journal of Organic Chemistry, 2013 , vol. 78, # 8 p. 4190 - 4195
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
El-Faham, Ayman; Chebbo, Mohamed; Abdul-Ghani, Mohamed; Younes, Ghassan
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 3 p. 599 - 606
反应条件
in dichloromethane T=20°C;
参考文献
El-Faham, Ayman; Chebbo, Mohamed; Abdul-Ghani, Mohamed; Younes, Ghassan
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 3 p. 599 - 606
反应条件
triethylamine in N,N-dimethyl-formamide 18 h; Heating;
参考文献
El-Faham, Ayman; Chebbo, Mohamed; Abdul-Ghani, Mohamed; Younes, Ghassan
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 3 p. 599 - 606
反应条件
in water T=160°C; 15 h; Yield given;
参考文献
Benassi, Rois; Grandi, Romano; Pagnoni, Ugo M.; Taddei, Ferdinando; Bocelli, Gabriele; Sgarabotto, Paolo
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1985 , p. 1513 - 1522
反应条件
1: aqueous HCl; POCl3 / 160 - 170 °C 2: 160 °C View Scheme
参考文献
Efros et al.
Zhurnal Obshchei Khimii, 1953 , vol. 23, p. 1691,1694; engl. Ausg. S. 1779, 1781
参考文献
Efros et al.
Zhurnal Obshchei Khimii, 1953 , vol. 23, p. 1691,1694; engl. Ausg. S. 1779, 1781
