1H-苯并三唑-1-甲醇合成路线 （共 47 条）
反应条件
1: SOCl2 / toluene / 2 h / Heating 2: 40 percent / methanol / 1 h / Heating 3: toluene; diethyl ether / Heating View Scheme
参考文献
Burckhalter et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 3868
反应条件
in acetic acid 3 h; Heating;
参考文献
Katritzky, Alan R.; Lan, Xiangfu; Lam, Jamshed N.
Synthesis, 1990 , p. 341 - 346
反应条件
hydrogenchloride in propan-1-ol 1.) reflux, 7.5 h 2.) room temp.;
参考文献
Synthesis, , p. 341 - 346
反应条件
1: 2-bromo-pyridine With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran T=-78°C; 1 h; 2: 1-Hydroxymethyl-1H-benzotriazole in tetrahydrofuran T=-78°C; 2 h;
参考文献
Deguest, Geoffrey; Bischoff, Laurent; Fruit, Corinne; Marsais, Francis
Organic Letters, 2007 , vol. 9, # 6 p. 1165 - 1167
反应条件
1: 60 percent / acetic acid / 0.25 h / Heating 2: 80 percent / methanol; H2O / 72 h / Heating View Scheme
参考文献
Synthesis, , p. 341 - 346
反应条件
in acetic acid 0.25 h; Heating;
参考文献
Katritzky, Alan R.; Lan, Xiangfu; Lam, Jamshed N.
Synthesis, 1990 , p. 341 - 346
反应条件
1: 2-picoline With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 1 h; 2: 1-Hydroxymethyl-1H-benzotriazole in tetrahydrofuran T=-78°C; 2 h;
参考文献
Deguest, Geoffrey; Bischoff, Laurent; Fruit, Corinne; Marsais, Francis
Organic Letters, 2007 , vol. 9, # 6 p. 1165 - 1167
反应条件
1: in ethanol T=20°C; 2: With sodium tetrahydroborate in ethanol 3: With sodium ethanolate in ethanol T=20°C; 48 h;
参考文献
Cytovia, Inc.
Patent: US2006/104998 A1, 2006 ;
Location in patent: Page/Page column 19 ;
US 20060104998 A1
参考文献
Katritzky, Alan. R.; Shobana, Navayath; Harris, Philip A.
Tetrahedron Letters, 1991 , vol. 32, # 34 p. 4247 - 4248
反应条件
1: phenylacetylene With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran T=-78°C; 1 h; 2: 1-Hydroxymethyl-1H-benzotriazole in tetrahydrofuran T=-78°C; 2 h;
参考文献
Deguest, Geoffrey; Bischoff, Laurent; Fruit, Corinne; Marsais, Francis
Organic Letters, 2007 , vol. 9, # 6 p. 1165 - 1167
