2-氯-2-(苯基亚肼基)乙酸乙醚合成路线 (共 18 条)
反应条件
sodium ethanolate in ethanol T=20°C; 3 h;
参考文献
Silvestri, Romano; Cascio, Maria Grazia; La Regina, Giuseppe; Piscitelli, Francesco; Lavecchia, Antonio; Brizzi, Antonella; Pasquini, Serena; Botta, Maurizio; Novellino, Ettore; Di Marzo, Vincenzo; Corelli, Federico
Journal of Medicinal Chemistry, 2008 , vol. 51, # 6 p. 1560 - 1576
反应条件
triethylamine; 3-phenyl-2-cyanothioacrylamide in ethanol 0.5 h; Ambient temperature;
参考文献
Abdelhamid, Abdou O.; Zohdi, Hussein F.; Rateb, Nora M.
Journal of Chemical Research, Synopses, 1995 , # 4 p. 144 - 145
反应条件
1: toluene / 2 h / |Reflux 2: sodium hydroxide; water / ethanol / 2 h / |Reflux View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 4 p. 1573 - 1582
反应条件
lithium hydroxide hydrate in ethylene glycol dimethyl ether T=20°C; 10 h; regioselective reaction;
参考文献
Sun, Aixue; Ye, Jia-Hai; Yu, Haitao; Zhang, Wenchao; Wang, Xiaolong
Tetrahedron Letters, 2014 , vol. 55, # 4 p. 889 - 892
反应条件
1: in toluene 2 h; Reflux; 2: With triethylamine in toluene
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 4 p. 1573 - 1582
反应条件
1: 65 percent / triethylamine / CHCl3 / 10 h / Heating 2: 70 percent / chloranil / xylene / 20 h / Heating View Scheme
参考文献
Hassaneen, Hamdi M.; Ead, Hamed A.; Elwan, Nehal M.; Shawali, Ahmed S.
Heterocycles, 1988 , vol. 27, # 12 p. 2857 - 2862
反应条件
triethylamine in ethanol T=20°C; 0.5 h;
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 179, # 11 p. 2221 - 2233
反应条件
1: 0.5 M NaOH / ethanol / 0.5 h / Ambient temperature 2: H2O / 7 h / Heating 3: 0.17 h / 300 °C View Scheme
参考文献
Abdelhamid, Abdou O.
Journal of Chemical Research, Miniprint, 1993 , # 6 p. 1239 - 1262
反应条件
1: 2,4(3H,5H)-Thiazoledione With potassium hydroxide in ethanol
1 h; Reflux;
2: oxalyl chloride phenylhydrazone ethyl ester in ethanol
1.5 h; Reflux;
参考文献
Matiychuk, Vasyl S.; Potopnyk, Mykhaylo A.; Luboradzki, Roman; Obushak, Mykola D.
Synthesis, 2011 , # 11 p. 1799 - 1803
反应条件
triethylamine in diethyl ether
48 h;
参考文献
Padwa, Albert; MacDonald, J. Gavin
Journal of Organic Chemistry, 1983 , vol. 48, # 19 p. 3189 - 3195