hydrogenchloride in water

potassium carbonate in acetone 48 h; Heating;

methanol; ion exchanger-resin

sulfuric acid T=0 - 25°C; 2 h; Product distribution / selectivity;

sulfuric acid Product distribution / selectivity;

diethyl ether; dichloromethane

Behandeln des Reaktionsprodukts mit Diazomethan in Aether;

1: chromium (VI)-oxide; aqueous acetic acid 3: Chromatographieren einer Loesung in Benzol an (alkalihaltigem) Aluminiumoxid View Scheme

1.1: 91 percent / P2O5 / CHCl3 / 8 h / 20 °C 2.1: 94 percent / LiAlH4 / tetrahydrofuran / 1.5 h / 20 °C 3.1: 100 percent / (COCl)2; DMSO; Et3N / CH2Cl2 / -78 °C 4.1: 97 percent / n-BuLi / tetrahydrofuran / 4.5 h / 20 °C 5.1: 89 percent / PPTS / 2-methyl-propan-2-ol / 10 h / Heating 6.1: TsCl; pyridine / 48 h / 0 °C 6.2: KOAc / dimethylformamide; H2O / 5 h / 105 °C View Scheme

1: With pyridine; p-toluenesulfonyl chloride 2: With potassium acetate in N,N-dimethyl-formamide T=110°C; 3: With potassium hydroxide in methanol T=110°C;