4-甲基噻吩-2-甲基羧酸盐合成路线 (共 14 条)
反应条件
1: LiAlH4 / diethyl ether 2: 75 percent / Li / various solvent(s) View Scheme
参考文献
Lozanova, A. V.; Moiseenkov, A. M.; Semenovskii, A. V.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 4 p. 619 - 623
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , # 4 p. 838 - 842
反应条件
lithium aluminium tetrahydride in diethyl ether Yield given;
参考文献
Lozanova, A. V.; Moiseenkov, A. M.; Semenovskii, A. V.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 4 p. 619 - 623
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , # 4 p. 838 - 842
反应条件
sodium hydroxide in tetrahydrofuran; methanol
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5840917 A1, 1998 ;
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane
2 h; Reflux;
参考文献
Hawker, Dustin D.; Silverman, Richard B.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 19 p. 5763 - 5773