反应条件
1.1: 1-methyl-piperazine / toluene / Heating 1.2: 5 h / Reflux 2.1: 5 Pd(II)/C(eggshell); hydrogen / 1,1-dimethylpropan-1-ol / 80 °C / 5171.62 Torr 3.1: 1,1-dimethylpropan-1-ol / 70 °C / Resolution of racemate; Large scale reaction 4.1: potassium carbonate / water; toluene / 6 h / 50 °C 5.1: dichloromethane / 2 h / -12 °C View Scheme
参考文献
Organic Process Research and Development, , vol. 15, # 5 p. 1010 - 1017
