5-溴-2-氯-3-甲氧基吡啶合成路线 （共 12 条）
反应条件
1: lithium hexamethyldisilazane / tetrahydrofuran / 20 °C
2: chloro-trimethyl-silane / 4 h / 65 °C
View Scheme
参考文献
Ple, Patrick A.; Jung, Frederic; Ashton, Sue; Hennequin, Laurent; Laine, Romuald; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Pasquet, Georges; Taylor, Sian
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 9 p. 3050 - 3055
反应条件
1: lithium hexamethyldisilazane / tetrahydrofuran / 20 °C
2: chloro-trimethyl-silane / 4 h / 65 °C
3: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 6 h / 85 °C
4: dihydrogen peroxide / dichloromethane / 1.5 h / 20 °C
View Scheme
参考文献
Ple, Patrick A.; Jung, Frederic; Ashton, Sue; Hennequin, Laurent; Laine, Romuald; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Pasquet, Georges; Taylor, Sian
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 9 p. 3050 - 3055
