N-苄氧羰酰基-D-苯丙氨酸合成路线 （共 27 条）
反应条件
cross-linked enzyme aggregates of Alcalase
T=50°C; 20 h; Molecular sieveEnzymatic reaction;
参考文献
Nuijens, Timo; Cusan, Claudia; Van Dooren, Theodorus J. G. M.; Moody, Harold M.; Merkx, Remco; Kruijtzer, John A. W.; Rijkers, Dirk T. S.; Liskamp, Rob M. J.; Quaedflieg, Peter J. L. M.
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 14-15 p. 2399 - 2404
反应条件
alcalase cross-linked enzyme aggregates
T=50°C; 48 h; Molecular sieveEnzymatic reaction;
参考文献
Nuijens, Timo; Piva, Elena; Kruijtzer, John A. W.; Rijkers, Dirk T. S.; Liskamp, Rob M. J.; Quaedflieg, Peter J. L. M.
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 7 p. 1039 - 1044
反应条件
copper diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene
2 h; Ambient temperature;
参考文献
Millington, Christopher R.; Quarrell, Rachel; Lowe, Gordon
Tetrahedron Letters, 1998 , vol. 39, # 39 p. 7201 - 7204
反应条件
sodium hydrogencarbonate
0.166667 h; Heating;
参考文献
Allevi, Pietro; Cighetti, Giuliana; Anastasia, Mario
Tetrahedron Letters, 2001 , vol. 42, # 31 p. 5319 - 5321
反应条件
1: 8 percent / 1 M EDTA, H2O / papain / CH2Cl2 / 24 h / 40 °C
2: 1 M EDTA, H2O / papain / CH2Cl2 / 24 h / 40 °C
View Scheme
参考文献
Braun; Kuhl
Pharmazie, 1997 , vol. 52, # 3 p. 203 - 206
反应条件
1: nitromethane / 0.08 h / Ambient temperature
2: nitromethane; tetrahydrofuran / 3 h / Ambient temperature
View Scheme
参考文献
Saha, Ashis K.; Schultz, Peter; Rapoport, Henry
Journal of the American Chemical Society, 1989 , vol. 111, # 13 p. 4856 - 4859
反应条件
potassium hydrogencarbonate in ethyl acetate
参考文献
Ito; Takahashi; Baba
Chemical and Pharmaceutical Bulletin, 1975 , vol. 23, # 12 p. 3081 - 3087
反应条件
1: phosphate buffer; α-chymotrypsin / dimethylsulfoxide / 1 h / -24 °C / pH 8.0
2: BF3*OEt2
View Scheme
参考文献
Salam, Sayed Mohiuddin Abdus; Kagawa, Ken-Ichi; Kawashiro, Katsuhiro
Tetrahedron Asymmetry, 2006 , vol. 17, # 1 p. 22 - 29
反应条件
triethylamine in ethyl acetate
参考文献
Itoh
Bulletin of the Chemical Society of Japan, 1974 , vol. 47, # 2 p. 471 - 475
反应条件
1: 10.8 percent / phosphate buffer; α-chymotrypsin / dimethylsulfoxide / 0.5 h / -24 °C / pH 8.0
2: BF3*OEt2
View Scheme
参考文献
Salam, Sayed Mohiuddin Abdus; Kagawa, Ken-Ichi; Kawashiro, Katsuhiro
Tetrahedron Asymmetry, 2006 , vol. 17, # 1 p. 22 - 29
