2-氯甲基-5-(4-甲基苯基)-1,3,4-恶二唑合成路线 (共 5 条)
反应条件
trichlorophosphate Reflux;
参考文献
Padmavathi; Dinneswara Reddy; Nagi Reddy; Mahesh
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1367 - 1373
反应条件
trichlorophosphate in acetonitrile 16 h; Reflux; Product distribution / selectivity;
参考文献
OSLO UNIVERSITY HOSPITAL HF; HOLSWORTH, Dan; WAALER, Jo; MACHON, Ondrej; KRAUSS, Stefan; GOLDING, Louise
Patent: WO2010/139966 A1, 2010 ;
Location in patent: Page/Page column 91-92; 102-103 ;
反应条件
1: tetrahydrofuran 2: POCl3 / 3 h / Heating View Scheme
参考文献
Moger, Manjunath; Satam, Vijay; Govindaraju, Darshan Raj C.; Paniraj; Gopinath, Vadiraj S.; Hindupur, Rama Mohan; Pati, Hari N.
Journal of the Brazilian Chemical Society, 2014 , vol. 25, # 1 p. 104 - 111
反应条件
1: N2H4*H2O 2: tetrahydrofuran 3: POCl3 / 3 h / Heating View Scheme
参考文献
Cao, Song; Qian, Xuhong; Song, Gonghua; Chai, Bing; Jiang, Zhisheng
Journal of Agricultural and Food Chemistry, 2003 , vol. 51, # 1 p. 152 - 155
反应条件
1: hydrazine hydrate; chloroformic acid ethyl ester / dichloromethane / 0 - 5 °C 2: ethyl acetate / |Reflux 3: trichlorophosphate / 80 °C View Scheme
参考文献
Moger, Manjunath; Satam, Vijay; Govindaraju, Darshan Raj C.; Paniraj; Gopinath, Vadiraj S.; Hindupur, Rama Mohan; Pati, Hari N.
Journal of the Brazilian Chemical Society, 2014 , vol. 25, # 1 p. 104 - 111