三-O-乙酰基-D- 葡萄烯糖合成路线 （共 170 条）
反应条件
1: 98 percent / H2O, NEt3 / methanol 2: 1) (Bu3Sn)2O, molecular sieves 3 Angstroem, 2) I2 / 1) CH3CN, 3 h, reflux, 2a) 5 deg C, 15 min, 2b) RT, 2 h View Scheme
参考文献
Reliable Biopharmaceutical Corporation
Patent: US2012/116066 A1, 2012 ;
反应条件
1: hydrolysis 2: pyridine View Scheme
参考文献
Holzapfel, Cedric W.; Engelbrecht, Gerhardus J.; Verdoorn, Gerhard H.
Heterocycles, 1989 , vol. 28, # 1 p. 433 - 444
反应条件
pyridine; triethylamine 1.) methanol, room temperature, 2.) 0 deg C, 3 min; Yield given. Multistep reaction;
参考文献
Holzapfel, C. W.; Marais, C. F.; Dyk, M. S. van
Synthetic Communications, 1988 , vol. 18, # 1 p. 97 - 114
反应条件
sodium methylate in methanol Yield given;
参考文献
Giese, Bernd; Groeninger, Kay
Tetrahedron Letters, 1984 , vol. 25, # 26 p. 2743 - 2746
反应条件
1: methanol; 3,4,6-tri-O-acetyl-D-glucal With urea hydrogen peroxide addition compound; methyltrioxorhenium (VII) T=20°C; 20 h; 2: acetic anhydride With pyridine T=20°C; 15 h;
参考文献
Goti, Andrea; Cardona, Francesca; Soldaini, Gianluca; Crestini, Claudia; Fiani, Cinzia; Saladino, Raffaele
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 4-5 p. 476 - 486
反应条件
1: 92 percent / BF3*OEt2 / toluene 2: 100 percent / triethylamine / methanol / 7 h / 70 °C 3: 99 percent / Pseudomonas lipase PS / 48 h / 20 °C 4: 100 percent / 1,8-diazabicyclo[5.4.0]-7-undecene / CH2Cl2 / 0.25 h / -17 °C 5: 54 percent / molecular sieves 4A / diphenyl ether / 0.58 h / 210 °C 6: 77 percent / ruthenium(III) chloride trihydrate; sodium metaperiodate / acetonitrile; ethyl acetate; H2O / 0.07 h / -11 °C 7: aq. sodium hydroxide / ethanol / 2 h / 30 - 40 °C 8: 42.8 mg / pyridine; DMAP / 20 °C 9: 87 percent / triethylamine / methanol / 7 h / 20 °C 10: 29.5 percent / diammonium cerium(IV) nitrate / acetonitrile; H2O / 2.17 h / 0 °C View Scheme
参考文献
Sugai, Takeshi; Okazaki, Hanako; Kuboki, Atsuhito; Ohta, Hiromichi
Bulletin of the Chemical Society of Japan, 1997 , vol. 70, # 10 p. 2535 - 2540
反应条件
1: 100 percent / K2CO3 / methanol / 12 h / 25 °C 2: 82 percent / imidazole / dimethylformamide / 1 h / 0 - 25 °C 3: 97 percent / Et3N; 4-DMAP / CH2Cl2 / 1 h / 0 - 25 °C View Scheme
参考文献
Nicolaou; Mitchell, Helen J.; Jain, Nareshkumar F.; Bando, Toshikazu; Hughes, Robert; Winssinger, Nicolas; Natarajan, Swaminathan; Koumbis, Alexandros E.
Chemistry - A European Journal, 1999 , vol. 5, # 9 p. 2648 - 2667
反应条件
methanol; potassium cyanide 3 h;
参考文献
Clark, J. Stephen; Hamelin, Olivier
Angewandte Chemie (International Edition in English), 2000 , vol. 39, # 2 p. X372-374
反应条件
tert-butyl methyl ether; Bacillus subtilis in various solvent(s) T=37°C; 60 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 5, # 22 p. 3657 - 3664
参考文献
Gehrke; Obst
Chemische Berichte, 1931 , vol. 64, p. 1724,1728
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Shafizadeh; Stacey
Journal of the Chemical Society, 1952 , p. 3608
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Overend; Stacey; Stanek
Journal of the Chemical Society, 1949 , p. 2845
