tetrakis(triphenylphosphine) palladium(0) Stille Coupling;

1: 2-bromo-6-methyl-pyridine With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: With zinc(II) chloride in tetrahydrofuran; hexane T=-78 - 20°C; 3: 6,6'-Dichloro-3,3'-bipyridazine With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; hexane Negishi Coupling Reaction; 48 h;

bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide T=95 - 105°C; Stille Coupling; 24 h; Product distribution / selectivity;