3-氯-1H-吲哚-2羧酸合成路线 （共 8 条）
反应条件
ethanol; sodium hydroxide 0.833333 h; Inert atmosphereReflux;
参考文献
Seifert, Katrin; Buettner, Anita; Rigol, Stephan; Eilert, Nicole; Giannis, Athanassios; Wandel, Elke
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6465 - 6481,17
反应条件
N-chloro-succinimide in acetonitrile 5 h; Reflux;
参考文献
Richter Gedeon Nyrt.; Beke, Gyula; Bényei, Gyula Attila; Borza, István; Bozó, Éva; Farkas, Sándor; Hornok, Katalin; Papp, Andrea; Vágó, István; Vastag, Mónika
Patent: US2013/217702 A1, 2013 ;
Location in patent: Paragraph 0114 ;
反应条件
1: phosphorus pentachloride 2: KOH-solution View Scheme
参考文献
Seifert, Katrin; Buettner, Anita; Rigol, Stephan; Eilert, Nicole; Giannis, Athanassios; Wandel, Elke
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6465 - 6481,17
反应条件
1: ammonium sulfide; alcohol / 100 °C 2: phosphorus pentachloride 3: KOH-solution View Scheme
参考文献
Gabriel; Gerhard; Wolter
Chemische Berichte, 1923 , vol. 56, p. 1024
反应条件
1: KOH-solution 2: ammonium sulfide; alcohol / 100 °C 3: phosphorus pentachloride 4: KOH-solution View Scheme
参考文献
Gabriel; Gerhard; Wolter
Chemische Berichte, 1923 , vol. 56, p. 1024
反应条件
1: alcohol 2: KOH-solution 3: ammonium sulfide; alcohol / 100 °C 4: phosphorus pentachloride 5: KOH-solution View Scheme
参考文献
Gabriel; Gerhard; Wolter
Chemische Berichte, 1923 , vol. 56, p. 1024
参考文献
Gabriel; Gerhard; Wolter
Chemische Berichte, 1923 , vol. 56, p. 1024
反应条件
1.1: N,N-dimethyl-formamide; thionyl chloride / 3 h / Reflux
1.2: 2 h / Cooling with ice
2.1: trichlorophosphate / chloroform / 3 h / Reflux
View Scheme
参考文献
Richter Gedeon Nyrt.; Beke, Gyula; Bényei, Gyula Attila; Borza, István; Bozó, Éva; Farkas, Sándor; Hornok, Katalin; Papp, Andrea; Vágó, István; Vastag, Mónika
Patent: US2013/217702 A1, 2013 ;
