2,7-二叔丁基-9-芴甲基氯甲酸酯合成路线 （共 4 条）
反应条件
in dichloromethane; toluene T=20°C; chloroacylation; 72 h;
参考文献
Stigers, Kimberly D.; Koutroulis, Mathew R.; Chung, De Michael; Nowick, James S.
Journal of Organic Chemistry, 2000 , vol. 65, # 12 p. 3858 - 3859
反应条件
1.1: 93 percent / FeCl3 / CS2 / 0 - 20 °C 2.1: n-BuLi / tetrahydrofuran; hexane / 0.13 h / 0 - 5 °C 2.2: 63 percent / tetrahydrofuran; hexane / 0.83 h / 0 - 20 °C 3.1: 100 percent / CH2Cl2; toluene / 72 h / 20 °C View Scheme
参考文献
Stigers, Kimberly D.; Koutroulis, Mathew R.; Chung, De Michael; Nowick, James S.
Journal of Organic Chemistry, 2000 , vol. 65, # 12 p. 3858 - 3859
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 0.13 h / 0 - 5 °C 1.2: 63 percent / tetrahydrofuran; hexane / 0.83 h / 0 - 20 °C 2.1: 100 percent / CH2Cl2; toluene / 72 h / 20 °C View Scheme
参考文献
Stigers, Kimberly D.; Koutroulis, Mathew R.; Chung, De Michael; Nowick, James S.
Journal of Organic Chemistry, 2000 , vol. 65, # 12 p. 3858 - 3859
参考文献
Chinchilla, Rafael; Dodsworth, David J; Najera, Carmen; Soriano, Jose M
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 14 p. 1817 - 1820
