N-[2-(2-噻吩基)乙基]甲酰胺合成路线 (共 4 条)
反应条件
PPA; trichlorophosphate
参考文献
Journal of the American Chemical Society, , vol. 77, p. 3529,3531
参考文献
Journal of the American Chemical Society, , vol. 77, p. 3529,3531
反应条件
ammonium hydroxide; sodium borohydride; iodine in tetrahydrofuran; methanol; sodium hydroxide; dichloromethane; tert-butyl methyl ether
参考文献
Novo Nordisk A/S
Patent: US5922770 A1, 1999 ;
反应条件
1: With triethylamine; trichlorophosphate in dichloromethane
T=0°C; Inert atmosphere;
2: With sodium carbonate in dichloromethane; water
1 h;
参考文献
Thompson, Mark J.; Chen, Beining
Journal of Organic Chemistry, 2009 , vol. 74, # 18 p. 7084 - 7093